*연구과제명: Psychological well-being and salivary markers of inflammation: The moderating effect of age
-연구 기관: 서울대학교 행복연구센터, 서울대학교 심리학과, 서울대학교 뇌인지과학과, 성균관대학교 바이오메디컬공학과, 기초과학연구원(IBS) 뇌과학이미징연구단, 성균관대학교 지능형정밀헬스케어융합전공, 연세대학교 사회학과, (연구팀)
-저자: 서울대학교 의과대학 및 서울특별시보라매병원 정신건강의학과서울
Abstract
Increasing evidence suggests a significant impact of higher psychological well-being (PWB) on health outcomes; however, such associations have been studied exclusively in middle-aged to older adults. This study examined the aging effect on PWB measures as well as the moderating effect of age on the link between PWB and inflammation, using salivary markers by comparing the younger adults (n = 127; Mage = 22.98 years) versus older adults (n = 75; Mage = 75.60 years). Older adults showed significantly lower levels of PWB, particularly regarding purpose in life and personal growth. Moreover, higher purpose in life was associated with lower salivary IL-1ß and IL-6 (b = 0.83, p < .001; b = 0.81, p < .01) only in the older adult group but not in younger adults. These findings highlight the potential buffering effect of the sense of living well on physiological pathways in later life.
KEYWORDS
aging effect, CRP, IL-1ß, IL-6, purpose in life, salivary inflammatory marker
*연구과제명: Psychological well-being and salivary markers of inflammation: The moderating effect of age
-연구 기관: 서울대학교 행복연구센터, 서울대학교 심리학과, 서울대학교 뇌인지과학과, 성균관대학교 바이오메디컬공학과, 기초과학연구원(IBS) 뇌과학이미징연구단, 성균관대학교 지능형정밀헬스케어융합전공, 연세대학교 사회학과, (연구팀)
-저자: 서울대학교 의과대학 및 서울특별시보라매병원 정신건강의학과서울
Abstract
Increasing evidence suggests a significant impact of higher psychological well-being (PWB) on health outcomes; however, such associations have been studied exclusively in middle-aged to older adults. This study examined the aging effect on PWB measures as well as the moderating effect of age on the link between PWB and inflammation, using salivary markers by comparing the younger adults (n = 127; Mage = 22.98 years) versus older adults (n = 75; Mage = 75.60 years). Older adults showed significantly lower levels of PWB, particularly regarding purpose in life and personal growth. Moreover, higher purpose in life was associated with lower salivary IL-1ß and IL-6 (b = 0.83, p < .001; b = 0.81, p < .01) only in the older adult group but not in younger adults. These findings highlight the potential buffering effect of the sense of living well on physiological pathways in later life.
KEYWORDS
aging effect, CRP, IL-1ß, IL-6, purpose in life, salivary inflammatory marker